On March 24, 2026, according to the official obituary from Suzhou Fengxue Wei and authoritative media, the well-known educator Zhang Xuefeng suddenly felt unwell after running at the company at 12:26 PM. He was sent to the hospital for emergency treatment but unfortunately passed away at 3:50 PM, at the age of only 41, due to cardiogenic sudden death .
He once used straightforward and relatable language to guide countless students on their paths to higher education and postgraduate studies. Now, his life has abruptly ended, shocking and regretting everyone. This tragedy once again warns us that cardiogenic sudden death is not far away, and even in prime age, potential heart issues should not be ignored.
Remark📝: There is a debate between the terms “cardiogenic sudden death” and “cardiogenic sudden death”. This article maintains consistency with the terminology used in textbooks, using “cardiogenic sudden death” in the main text.
How Close is Sudden Death to Us?
According to statistics, approximately 544,000 people die from cardiomyogenic sudden death in China each year, with an incidence rate of about 41.8 per 100,000 people.
What does this number mean?
It is in the same order of magnitude as lung cancer (about 30-60/100,000) and acute myocardial infarction (about 87.6/100,000) . This means that sudden death is not a “low-probability” issue of “luck”, but like these major diseases, it is a serious public health challenge facing contemporary China.
However, we do not need to panic excessively.
In comparison, the incidence of stroke (cerebral infarction) is (247-491/100,000) 5 to 10 times that of sudden death. This means that with a large population base, as long as we understand the risk factors, this risk is within an observable and manageable range.
Faced with the sudden death of celebrities, the deepest fear of the public often comes from a sense of “life being uncontrollable”. However, from a medical perspective, sudden death is not a “random event” without any signs.
In medical terms, sudden death (especially cardiomyogenic sudden death) is defined as sudden and unexpected death caused by heart disease, usually occurring within 1 hour after the onset of symptoms. This definition emphasizes “sudden” and “unexpected” rather than being completely “without warning”.
Studies have found that about 50-75% of sudden death patients have recognizable warning symptoms in the 4 weeks before the event, including chest pain, difficulty breathing, nausea and vomiting, dizziness or fainting, etc., two-thirds of which last more than 1 hour.
The most common preceding symptoms are angina (22%) and difficulty breathing (15%) . However, only about 21% of patients with symptoms will contact the emergency system.
Therefore, the more accurate understanding of “without warning” should be: The patient or those around them fail to recognize or take these warning symptoms seriously, rather than there being no signs at all.
These preceding symptoms are like the “final warning” from the heart. If they can be captured in time, the risk can often be stopped in its tracks:
Unexplained chest tightness and palpitations: Especially the feeling of oppression related to exertion and emotional excitement;
Abnormal fatigue and blackouts: Even with sufficient sleep, one still feels extremely physically exhausted, or suddenly seeing black;
Difficulty breathing: A significant decrease in exercise tolerance in a short period of time.
Some of these signals may seem familiar: discomfort after exertion or emotional excitement, fatigue even with sufficient sleep, and seeing black . In today’s fast-paced society, many professionals have experienced similar feelings.
So, how many of them really indicate heart risks? When we feel unwell, what situations can we just rest and be fine, and what situations require seeking a doctor’s help?
Self-assessment: Is it “just too tired” or is the “heart crying for help”?
Chest pain during late nights and discomfort in the chest when feeling stressed, which goes away after rest, is it really a heart problem?
The physiological structures involved in the chest area are quite complex, and any abnormality in these structures may cause chest pain.
Heartbeat, breathing, eating, moving, and other activities also involve chest structures, and any abnormality in these activities may also cause chest pain and discomfort.
For further reading👉:Does a sudden chest pain mean there is a heart problem? What to do?
Therefore, not all chest pain is related to the heart, and not all chest pain indicates a fatal disease.
Data from JAMA shows the types of chest pain encountered in American emergency departments and their distribution across different ages. From left to right, the proportion of cardiomyogenic chest pain increases with age, and over the age of 65, the chest pain caused by basic heart problems also gradually increases; while before the age of 45, the proportion of cardiomyogenic chest pain is far less than 5%.
Therefore, not all chest pain indicates an imminent cardiac event, but remember, chest pain must be checked to determine if it is a dangerous event.
We can refer to the “Chest Pain Traffic Light” recommended by the American Heart Association (AHA) for classification and processing:
Chest Pain Traffic Light🚥
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Green (Low Risk) : Unfixed location, tearing sensation, stabbing pain, related to breathing or posture. It is recommended to maintain a regular schedule and observe primarily.
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Yellow (Moderate Risk) : Dull pain, soreness, position slightly to the left. It is recommended to make an appointment with a cardiologist for routine screening.
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Red (High Risk) : Oppressive sensation behind the sternum, colic pain, accompanied by cold sweat. Must immediately stop activities and seek medical help.
The following figure: Myocardial ischemic chest pain traffic light reference diagram shows that the redder, the more dangerous it is, and the greener, the lower the correlation with myocardial ischemia.
Which situations require immediate medical attention?
If any of the following situations occur, do not wait for the symptoms to subside on their own and go to the nearest emergency department or dial 120 immediately:
Attention⚠️
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Persistent chest pain : Severe oppressive pain lasting more than 15 minutes.
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Accompanying systemic symptoms : Chest pain accompanied by pale complexion, profuse sweating, difficulty breathing, or a sense of impending death.
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Change in mental status : Sudden blackouts (blacking out) , syncope, or brief loss of consciousness.
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Unstable vital signs : Sudden drop in blood pressure (systolic pressure, i.e., “high pressure,” <90mmHg) or extremely irregular, too fast/slow pulse.
In the field of cardiology, “time is myocardium”.
Taking the most common acute myocardial infarction as an example, about half of the ischemic myocardium progresses to necrosis within 40 minutes after coronary occlusion, and one-third of the myocardium can still be salvaged after 3 hours, and the process of myocardial necrosis is basically completed after 6 hours.
Early opening of blocked vessels can maximize the salvage of necrotic myocardium and prevent cardiac arrest. Clinical studies have confirmed that reperfusion completed within 90 minutes (from the first medical contact to the opening of the vessel) can achieve the maximum myocardial salvage. For every 60-minute delay in reperfusion treatment, the mortality rate increases by about 10%.
The latest national registry study in the United States (2018-2021) shows that patients who achieve treatment time targets have significantly reduced in-hospital mortality. For patients transported by emergency medical services, the mortality rate is 3.3% for those with first medical contact to vessel opening ≤90 minutes, while the mortality rate is as high as 12.1% for those exceeding 90 minutes.
Many tragedies occur because patients harbor a “wait and see” or “go to the hospital at dawn” mentality, missing the golden window of treatment.
How can doctors help you?
For acute chest pain (especially chest pain at rest, persistent chest pain, accompanied by difficulty breathing/sweat/nausea, etc.) , it is best to call the emergency number (120) instead of going to the hospital on your own.
The emergency medical system can perform electrocardiogram examinations on the way, notify the hospital in advance, and directly transfer to hospitals with intervention capabilities when diagnosing ST-segment elevation myocardial infarction (STEMI), greatly reducing treatment time.
Patients visiting the emergency department may undergo a series of examinations in a certain order and priority:
Examination order and priority
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Electrocardiogram : Completed within 10 minutes (Top priority) , the most basic and fastest method. It can identify arrhythmias (e.g., premature beats, atrial fibrillation) or ongoing myocardial ischemia.
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High-sensitivity troponin : Blood test as soon as possible, those with initial normal values need to be rechecked after 1-3 hours. Troponin is a “specific indicator” of heart damage, and once elevated, it usually means that myocardial cells are suffering damage.
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Bedside ultrasound/echocardiogram : Observe the structure and size of the heart as well as valve function. It can rule out hidden structural abnormalities, such as hypertrophic cardiomyopathy, which is a common cause of sudden death in young people during exercise.
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Holter monitoring : If symptoms are intermittent, the ordinary electrocardiogram cannot capture them, the 24-hour monitor can record the heart’s electrical activity during work, sleep, and stress.
In some cases, emergency coronary angiography and interventional treatment are needed. Before these invasive examinations and treatments, doctors will inform the risks and seek informed consent from the patients and their families. Time is life, at critical moments, please choose to trust the doctors:
Emergency Coronary Angiography and Interventional Treatment
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ST-segment elevation myocardial infarction (STEMI) : Electrocardiogram shows ST-segment elevation, and percutaneous coronary intervention (PCI) should be completed within 120 minutes, which can reduce the mortality rate from 9% to 7%
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High-risk non-ST-segment elevation acute coronary syndrome (NSTE-ACS) : Including troponin positivity, new ischemic changes on electrocardiogram, hemodynamic instability, new-onset left ventricular dysfunction, etc., coronary angiography should be performed within 24-48 hours.
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Persistent chest pain with ST-segment depression or new wall motion abnormalities : Requires immediate coronary angiography and revascularization.
Emergency assessment should not only consider heart problems but also exclude other life-threatening conditions, including: aortic dissection, pulmonary embolism, myocarditis, esophageal rupture, tension pneumothorax, etc.
Bedside ultrasound, chest X-ray, and continuous electrocardiogram are very valuable for identifying these diseases. Sometimesrepeating different examinations,the same examinationmultiple times, may be necessary.
Can Cardiomyogenic Sudden Death Be Prevented?
For ordinary people, it is better to establish a rational medical understanding rather than anxiety in the sigh of “the impermanence of all things”.
The etiology of cardiomyogenic sudden death is complex and diverse, and often not singular, including various cardiovascular diseases, adverse living conditions and habits, chronic diseases are common risk factors .
For example, poor dietary habits (smoking, excessive drinking, overeating, intake of too much high-fat food, etc.) , poor lifestyle (staying up late, lack of exercise, obesity, etc.) , excessive work and mental stress, etc. For chronic diseases, such as hypertension, diabetes, chronic kidney disease, dyslipidemia, proteinuria, metabolic syndrome, etc.
Just like stacking buffs, the more risk factors accumulated, the more dangerous it is. Reliable prevention methods include trying to change bad living and dietary habits, maintaining a healthy and regular lifestyle, having regular check-ups, actively treating and improving health conditions, keeping physically and mentally happy, and seeking medical help and doctors’ assistance when symptoms appear.
Please keep the following two self-check lists:
Cardiac Health High-Risk Factor Self-Check List (Young and Middle-aged Edition)
Please assess your physical/family conditions over the past year and currently. Studies show that 65%-78% of sudden death cases aged 18-50 have at least one of the following cardiovascular risk factors. If you meet 3 or more, it is recommended to consult a cardiologist for a professional cardiovascular risk assessment.
1. Family and Past Medical History (Uncontrollable Factors)
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Early-onset cardiovascular disease family history: Among immediate relatives, men under 55 and women under 65 have coronary heart disease, myocardial infarction, or sudden death.
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Known chronic diseases: Diagnosed with hypertension, hyperglycemia (diabetes or impaired glucose tolerance) , hyperlipidemia.
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Other disease history: Suffering from chronic kidney disease or autoimmune diseases (e.g., systemic lupus erythematosus) , these diseases significantly accelerate vascular endothelial damage and aging.
2. Lifestyle (Controllable Factors)
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Tobacco dependence: Currently smoking or long-term exposure to secondhand smoke.
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Insufficient physical activity: Less than 150 minutes of moderate-intensity exercise (such as brisk walking, jogging) per week.
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Sleep and breathing disorders: Average daily sleep less than 6 hours, or with severe snoring, sleep apnea (OSA) .
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High-stress state: Long-term high-intensity mental labor, emotional anxiety, and continuous excitement of the sympathetic nervous system.
3. Clinical Indicators (Dynamic Monitoring)
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Abdominal obesity: Men with waist circumference ≥ 90cm, women with waist circumference ≥ 85cm.
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Hypertension criteria: According to the latest guidelines, systolic blood pressure ≥ 130 mmHg or diastolic blood pressure ≥ 80 mmHg is defined as hypertension, not just blood pressure fluctuations.
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Resting heart rate:>80 beats per minute. Note: Although a very high heart rate is associated with risk, it is no longer used as an independent and clear risk threshold in clinical practice, only as a reference.
4.Key Warning Signs (Needing High Attention)
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Exertional chest oppression: Feeling a sense of oppression in the chest when climbing stairs, walking fast, or carrying loads, which can be relieved after rest.
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Unexplained blackouts/syncope: Suddenly seeing black or having a history of brief loss of consciousness.
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Palpitations/arrhythmia: Experiencing noticeable skipped beats, rapid heartbeat, or significant rhythm disturbances.
Annual Physical Examination Suggestions for Workplace Population
For young and middle-aged workplace populations aged 30-50, it is recommended to add special examinations based on individual risk stratification in addition to routine physical examinations.
1. First Tier: Basic Required Items (Annual Standard Screening)
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Blood Pressure Measurement: It is recommended to measure both arms to identify occult hypertension.
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Lipid Panel: The core indicator is LDL-C (low-density lipoprotein cholesterol) .
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Metabolic Assessment: Including fasting blood sugar and glycated hemoglobin (HbA1c) , to assess long-term blood sugar control.
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Routine Electrocardiogram (ECG) : Preliminary screening for arrhythmias and old myocardial damage.
2. Second Tier: Targeted Special Examinations (Symptomatic or High-Risk Population)
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Echocardiogram (UCG): :
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Not for general screening: : Not recommended for low-risk populations without symptoms or risk factors for routine examination.
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Indications: : Those with the above warning signs, auscultation findings of murmurs during physical examination, abnormal electrocardiograms, or a family history of hereditary cardiomyopathy.
24-hour ambulatory electrocardiogram (Holter) :
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Significance: : Suitable for people with intermittent palpitations and chest tightness, but no abnormalities captured by outpatient electrocardiograms.
3. Third Tier: In-depth Risk Stratification (Specific High-Risk Population)
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Coronary Artery Calcium Score (CAC) :
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Value: Currently recognized as the most valuable non-invasive risk assessment tool. CAC=0 indicates a very low cardiovascular risk in the next 5-10 years; CAC>300 indicates high risk.
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Special Reminder ⚠️: Limited value in people under 40 years old, as coronary artery calcification has not yet formed in young people, and even a score of 0 does not mean no plaque.
Carotid Ultrasound: :
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Significance: By assessing carotid plaque conditions, it reflects the burden of systemic atherosclerosis. Although not routinely recommended by all guidelines, it helps with further risk stratification.
Biomarkers (NT-proBNP / hs-cTn) :
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Not recommended for general screening: : Due to low positive predictive value and influenced by age, renal function, and other factors, not recommended for routine screening in asymptomatic general populations.
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Specific use: : Only recommended for annual condition monitoring in patients with diabetes, chronic kidney disease, or left ventricular hypertrophy.
4. Pre-exercise Assessment Recommendations
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Exercise stress test (treadmill ECG) :
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Not recommended for routine screening of low-risk, asymptomatic adults. .
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Recommended population: High-risk middle-aged and elderly people (especially those with diabetes) planning to participate in high-intensity endurance sports (such as marathons) , those with multiple risk factors or significantly elevated CAC scores, and those with suspected symptoms.
Athlete screening: :
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For people under 35 years old planning to participate in competitive sports, the American guidelines (AHA/ACC) recommend medical history and physical examination as the basic screening, but do not recommend routine electrocardiogram screening; while the European guidelines (ESC) suggest adding a 12-lead electrocardiogram screening. Both options have their pros and cons and can be chosen based on actual situations.
The sudden passing of Mr. Zhang Xuefeng reminds us once again that health is never taken for granted, and being in the prime of life does not mean being “invincible”.
Whether it is striving for a career or pursuing dreams, it must be based on cherishing one’s body: Maintain a regular schedule, avoid staying up late, exercise moderately, learn to relieve stress, have regular check-ups, especially pay attention to heart health, and those with a history of underlying diseases must follow medical advice for treatment.
May the deceased rest in peace, and may everyone who works hard to live treat their heart well and stay away from this sudden parting.
Peer Review Expert Guo Xiao
Internal Medicine and Cardiovascular Physician at Distinct Health
Ph.D. from Peking Union Medical College
References
Content Editor Luka
Disclaimer: The article is intended to provide general health information. For personal medical issues, please consult a doctor. To republish the article, please contact: medicine@distinctclinic.com.

